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Cured How the Berlin Patients Defeated HIV and Forward-Looking Scientific Insights
"The Berlin patients achieved functional or sterilizing cures from HIV primarily through allogeneic hematopoietic stem cell transplantation utilizing donor cells carrying a rare homozygous CCR5 delta-32 genetic mutation. This rare physiological adaptation prevents human immunodeficiency virus type 1 from entering target immune cells, setting a monumental precedent in medical history for viral eradication. Introduction to the Berlin Patients and the Concept of an HIV Cure For decades, human immunodeficiency virus (HIV) was considered an incurable chronic infection requiring lifelong antiretroviral therapy (ART) to suppress viral replication and..."
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