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The Pineal Gend and Cancer: Biological Mechanisms, Melatonin Interactions, and Clinical Research in 2026
"The relationship between the pineal gland and cancer represents a fascinating intersection of neuroendocrinology, oncology, and circadian biology. Positioned deep within the epithalamus, this small, pinecone-shaped endocrine gland primarily synthesizes and secretes melatonin, a vital hormone that regulates the sleep-wake cycle and orchestrates complex systemic immunomodulatory and oncostatic functions. As clinical research progresses into 2026, medical oncologists and neuroendocrinologists are increasingly exploring how pineal dysfunction, altered melatonin signaling, and circadian disruption contribute to tumorigenesis, cancer progression, a..."
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