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Rickets Explained: Clinical Pathophysiology, Diagnosis, and Management Protocols for 2026
"Rickets is a classic metabolic bone disorder characterized by the defective mineralization of the cartilaginous growth plates in children and growing animals before the fusion of the epiphyses. Unlike osteomalacia, which affects the already mineralized adult skeleton, rickets targets actively growing bones, resulting in structural deformities, growth retardation, and characteristic skeletal pain. As pediatric metabolic and nutritional guidelines evolve in 2026, clinicians continue to encounter this condition due to a combination of rising nutritional deficiencies, exclusive breastfeeding practices without adequate vitamin D supplementation, a..."
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