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Evolution and Clinical Efficacy: Photodynamic Tumor Therapy 2nd and 3rd Generation

"Photodynamic therapy (PDT) is a sophisticated, light-activated medical treatment that selectively targets and destroys malignant cells while sparing healthy tissue. The transition from 1st-generation agents, which were limited by long-lasting systemic photosensitivity, to 2nd and 3rd-generation photosensitizers represents a clinical evolution toward higher tumor selectivity, deeper tissue penetration, and improved patient recovery profiles in modern oncology. Understanding the Mechanism of Photodynamic Therapy At its core, photodynamic therapy relies on a triad: a non-toxic photosensitizing agent (PS), a specific wavelength of light, and tiss..."

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